publication

Improving mitochondria-associated endoplasmic reticulum membranes integrity as converging therapeutic strategy for rare neurodegenerative diseases and cancer

Membrane contact sites harbor a distinct set of proteins with varying biological functions, thereby emerging as hubs for localized signaling nanodomains underlying adequate cell function.

Improving mitochondria-associated endoplasmic reticulum membranes integrity as converging therapeutic strategy for rare neurodegenerative diseases and cancerchloeSitera2026-06-04T15:32:28+00:00

Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models

Abstract The Wolfram syndrome is a rare autosomal recessive [...]

Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical modelschloeSitera2026-06-04T15:32:54+00:00

ER-mitochondria cross-talk is regulated by the Ca2+sensor NCS1 and is impaired in Wolfram syndrome

Abstract Communication between the endoplasmic reticulum (ER) and mitochondria [...]

ER-mitochondria cross-talk is regulated by the Ca2+sensor NCS1 and is impaired in Wolfram syndromechloeSitera2026-06-04T15:37:33+00:00